Biological Activities of Alpha1-fetoprotein
نویسندگان
چکیده
منابع مشابه
Ultrastructural detection of alpha1-fetoprotein in hepatomas by use of peroxidase-labelled antibodies.
Hepatomas were induced in rats by feeding N-nitrosomorpholine. Nodules from alpha1-fetoprotein (AFP)-producing hepatoma were taken and subcutaneously injected into syngeneic hosts. From the first generation, the hepatoma producing most AFP was selected for further transfers. Four weeks after transplantation, the AFP concentration in the host rats was in the range of 0.8 to 1.5 mg AFP/ml serum. ...
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Leupeptins, leupeptin Pr and leupeptin Ac, strongly inhibit proteolysis by plasmin, trypsin and papain, but do not inhibit proteolysis by <#-chymotrypsin. The inhibition is competitive with substrates. The inhibitory effect on esterolysis by plasmin and trypsin is weaker than on proteolysis. The results with derivatives of leupeptins which contain carboxyl or alcohol instead of aldehyde and of ...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1988
ISSN: 1468-6244
DOI: 10.1136/jmg.25.11.790-a